Application of sequential cyclic compression on cancer cells in a ...

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Sensor readings in s1 movie showed that the micro-piston ... cell groups after compression suggests that cells exists that show no full.
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ApplicationofsequentialcycliccompressiononcancercellsinaflexiblemicrodeviceSevgiOnal1,2*,MaanM.Alkaisi1,2,andVolkerNock1,2,3*1ElectricalandComputerEngineering,UniversityofCanterbury,Christchurch,NewZealand2MacDiarmidInstituteforAdvancedMaterialsandNanotechnology,Wellington,NewZealand3BiomolecularInteractionCentre,UniversityofCanterbury,Christchurch,NewZealand*[email protected]@canterbury.ac.nzAbstractMechanicalforcesshapephysiologicalstructureandfunctionwithincellandtissuemicroenvironments,duringwhichcellsstrivetorestoretheirshapeordevelopanadaptivemechanismtomaintaincellintegritydependingonstrengthandtypeofthemechanicalloading.Whilesomecellsareshowntoexperiencepermanentplasticdeformationafterarepetitivemechanicaltensileloadingandunloading,theimpactofsuchrepetitivecompressiononplasticdeformationofcellsisyettobeunderstood.Assuch,theabilitytoapplycycliccompressioniscrucialforanyexperimentalsetupaimedatthestudyofmechanicalcompressiontakingplaceincellandtissuemic...