/ 0
60%
Table of contents

Document in text mode:

ApplicationofsequentialcycliccompressiononcancercellsinaflexiblemicrodeviceSevgiOnal1,2*,MaanM.Alkaisi1,2,andVolkerNock1,2,3*1ElectricalandComputerEngineering,UniversityofCanterbury,Christchurch,NewZealand2MacDiarmidInstituteforAdvancedMaterialsandNanotechnology,Wellington,NewZealand3BiomolecularInteractionCentre,UniversityofCanterbury,Christchurch,NewZealand*[email protected]@canterbury.ac.nzAbstractMechanicalforcesshapephysiologicalstructureandfunctionwithincellandtissuemicroenvironments,duringwhichcellsstrivetorestoretheirshapeordevelopanadaptivemechanismtomaintaincellintegritydependingonstrengthandtypeofthemechanicalloading.Whilesomecellsareshowntoexperiencepermanentplasticdeformationafterarepetitivemechanicaltensileloadingandunloading,theimpactofsuchrepetitivecompressiononplasticdeformationofcellsisyettobeunderstood.Assuch,theabilitytoapplycycliccompressioniscrucialforanyexperimentalsetupaimedatthestudyofmechanicalcompressiontakingplaceincellandtissuemic...