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APPRAISALOFGUIDELINESFORRESEARCH& EVALUATIONINSTRUMENTThe AGREE Collaboration September 2001 COPYRIGHT AND REPRODUCTIONThis document is the product of an international collaboration. It may be reproduced and used for educational purposes, quality assurance programmes and critical appraisal of clinicalpractice guidelines. It may not be used for commercial purposes or product marketing. Approved non-English language versions of the AGREE Instrument are being prepared, and must be used where available. Offers of assistance in translation into other languages are welcome, provided they conform to the protocol set out by the AGREE Collaboration.DISCLAIMERThe AGREE Instrument is a generic tool designed primarily to help guideline developers and users assess the methodological quality of clinical practice guidelines. The authors do not take responsibility for the improper use of the AGREE Instrument.© St George’s Hospital Medical School, London, June 2001Reprinted with amendments September 20...